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Ch 8 · Airway

Difficult Airway Algorithm

ASA algorithm: anticipate, prepare, ventilate. Patients die from hypoxemia, not failed intubation.

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Key Points

  • Patients die from lack of OXYGENATION — not from failed intubation. Always default to whatever oxygenates.
  • Difficult mask ventilation is more dangerous than difficult intubation.
  • Predictors of difficult MV (MaMaBOATS): Mallampati III/IV, ↓ Mandibular protrusion, Beard, Obesity, Age > 57, Teeth (lack), Snoring.
  • Proper sniffing position: align tragus to sternum, parallel to floor. Ramp obese patients.
  • Call for help EARLY. Surgical airway last but don't postpone when needed.

01Definition

Per ASA: "A clinical situation in which a conventionally trained anesthesiologist experiences difficulty with facemask ventilation of the upper airway, difficulty with tracheal intubation, or both."

Patients do not die from failed intubation — they die from lack of oxygenation. If the pulse ox is dropping, fall back to whatever lets you oxygenate.

02ASA Algorithm — High-Level Steps

  1. Assess likelihood and impact of:
  2. - Difficulty with patient cooperation/consent
  3. - Difficult mask ventilation
  4. - Difficult supraglottic airway placement
  5. - Difficult laryngoscopy / intubation
  6. - Difficult surgical airway access
  7. Actively oxygenate throughout the process.
  8. Consider awake vs asleep, non-invasive vs invasive, video-laryngoscopy first, preserve vs ablate spontaneous ventilation.
  9. Develop primary and alternative strategies.
  10. Call for help early.
  11. After failed intubation: SGA → fiberoptic through SGA → wake / surgical airway.

03Predictors of Difficult Mask Ventilation

MaMaBOATS (any 3 = high risk): - Mallampati III or IV - Mandibular protrusion decreased - Beard - Obesity (BMI > 30) - Age > 57 - Teeth (lack of) - Snoring (OSA)

Predictors of IMPOSSIBLE mask ventilation (MaMaBORa): Mallampati III–IV, Males, Beard, OSA / upper airway surgery, Radiation changes to neck.

04Predictors of Difficult Intubation

Successful direct laryngoscopy requires aligning oral, pharyngeal, and laryngeal axes.

  • Mallampati III or IV
  • Short, thick neck
  • Thyromental distance < 3 finger breadths
  • Inter-incisor distance < 3 cm (small mouth opening)
  • Prominent overbite
  • Decreased TMJ mobility; inability to prognath
  • Limited cervical range of motion
  • High-arched / narrow palate
  • Poor submandibular compliance (mass, infection, radiation)
  • Underlying pathology (laryngeal stenosis, epiglottitis, tumor)

History of prior airway difficulty is the single most important predictor — always check old records.

05Sniffing Position

Requires flexion at C7 and extension at C5-C6. - Ramp obese patients until the line between the tragus and sternal notch is parallel to the floor. - For neonates and infants, place a roll under the shoulders (large occiput causes neck flexion). - Poor positioning can turn a Cormack-Lehane grade 1 view into a grade 4 view.

Proper positioning is worth your effort, even at the start of an emergent case.

06Oxygenation Options

  • Mask ventilate in sniffing position
  • Oral airway (Guedel) or nasal trumpet (caution with skull-base fracture, coagulopathy)
  • Supraglottic airway (LMA)
  • Nasal cannula apneic oxygenation (high-flow nasal: Optiflow, THRIVE 30–70 L/min) — extends safe apnea time
  • During fiberoptic: endoscopic mask (Patil-Syracuse) for PPV, or swivel adapter on ETT
  • Rigid bronchoscope side port
  • Jet ventilation (specialized airways, beware barotrauma)

07Awake Intubation

Indications: known/predicted difficult airway, unstable c-spine, severe airway pathology (tumor, abscess, edema).

Key is topicalization: - Antisialagogue: glycopyrrolate 0.2 mg IV/IM ~30 min ahead - Sedation: dexmedetomidine, low-dose midazolam, ketamine — preserve spontaneous ventilation - Local anesthetic options: - 4% lidocaine nebulized (5–10 min) - 4% lidocaine atomized or via mucosal atomizer - Cetacaine spray (benzocaine — methemoglobinemia risk) - Transtracheal injection (2% lido through cricothyroid membrane) - Superior laryngeal nerve block (above hyoid bone) - Glossopharyngeal nerve block (lateral oropharynx)

Techniques: flexible bronchoscopy (FOB), video laryngoscopy (awake AWS, GlideScope), retrograde wire, lighted stylet.

08Surgical Airway

From an ENT chief resident: "Even in an emergency, always invest 20 seconds to:" - Identify someone to assist - Position the patient (extend the neck, palpate the cricothyroid membrane) - Have a 6.0 ETT and scalpel ready

Cricothyrotomy (preferred over tracheostomy emergently): 1. Scalpel — vertical skin incision over cricothyroid membrane 2. Horizontal stab through the membrane 3. Bougie introduced caudally 4. Railroad 6.0 ETT over bougie

Confirm: EtCO₂, bilateral breath sounds, no subcutaneous emphysema with positive-pressure ventilation.

References & Further Reading

  1. 1
    GuidelineOpen source

    Apfelbaum JL, Hagberg CA, Connis RT, et al. 2022 American Society of Anesthesiologists Practice Guidelines for Management of the Difficult Airway. Anesthesiology. 2022;136(1):31-81.

  2. 2
    Journal

    Cook TM, Woodall N, Frerk C; Fourth National Audit Project. Major complications of airway management in the UK (NAP4). Br J Anaesth. 2011;106(5):617-642.

  3. 3
    Textbook

    Gropper MA, Miller RD, Cohen NH, et al., eds. Miller's Anesthesia. 9th ed. Philadelphia: Elsevier; 2020.

  4. 4

    Stanford Anesthesia Cognitive Aid Group. Stanford Anesthesia Emergency Manual. emergencymanual.stanford.edu.

  5. 5
    Textbook

    Adriano A, Morris R, eds. 2021 CA-1 Tutorial Textbook (15th Ed.). Stanford University Medical Center, Department of Anesthesiology.

Citations are provided to direct further study. Always check the most current edition of guidelines and society recommendations — the information in this chapter is a teaching summary, not primary source material.