OR Playbook
Step 27 · Subspecialty

Obstetric Anesthesia — The Basics

Pregnancy physiology, labor epidurals, and anesthesia for C-section.

8 min read

The TL;DR

  • Pregnancy lowers MAC, makes the airway friable/edematous, drops FRC (rapid desaturation), raises CO, and lowers SVR.
  • Treat every pregnant patient as a full stomach, and always use left-uterine displacement (bump under the right hip) to avoid aortocaval compression.
  • Labor analgesia is usually a dilute local ± opioid epidural infusion; watch for hypotension (nausea is often the first sign).
  • A C-section is full abdominal surgery under regional — be ready to convert to GA, and run a full machine/room check.
  • The OB airway is difficult until proven otherwise — thorough exam, smaller ETT, most experienced intubator.

01Physiology of pregnancy

Pregnancy changes nearly every system relevant to anesthesia:

  • Neuro: MAC is decreased. Engorged epidural veins shrink the epidural space and CSF volume → local anesthetic spreads more near term (use less).
  • Respiratory: the airway is friable and edematous (often needs a smaller cuffed ETT); FRC falls while O₂ consumption rises → rapid desaturation on induction; tidal volume and minute ventilation rise.
  • Cardiovascular: ↑ blood volume, ↑ cardiac output (can jump ~80% right after delivery), ↓ SVR.
  • Aortocaval compression: supine, the gravid uterus compresses the IVC and aorta → put a bump under the right hip (~15 cm) for left-uterine displacement.
  • GI: increased reflux and a full stomach (slow motility) → aspiration risk. Treat every pregnant patient as a full stomach.
Pearls
  • Left-uterine displacement is comfort + physiology — it improves venous return and BP, not just comfort.

02Labor epidurals

The anesthesia team places and manages the labor epidural — typically a dilute local anesthetic ± opioid infusion, seated or in the left lateral position. Check the level periodically (ice or a pin) for the dermatome of analgesia.

Complications: - Hypotension (the most common) — sympathetic blockade → ↓SVR/BP. Nausea is often the first sign. Pre-treat with IV fluid; treat with left-uterine displacement, fluids, and a vasopressor (phenylephrine or ephedrine). - High spinal / high epidural — block higher than intended → trouble breathing, unconsciousness, CV collapse. Turn the infusion down, communicate; a total spinal means intubate and support the patient while monitoring fetal tones. - Slowed labor — you may be asked to turn the rate down for the second stage.

03Anesthesia for C-section

Don't be fooled — a C-section is full abdominal surgery, usually under regional (dose up a working epidural, or place a spinal/combined spinal-epidural). Be ready to convert to general if the patient becomes unstable or the block fails — run a full machine/room check so the equipment is ready.

  • Aspiration prophylaxis: metoclopramide (motility), an H₂ blocker like cimetidine (acid), sodium citrate PO (neutralize acid).
  • After delivery: oxytocin (after the placenta); methylergonovine IM for uterine atony if asked; deepen volatile if the surgeon needs uterine relaxation.
  • If general is needed: the OB airway is difficult until proven otherwise — thorough airway exam, smaller ETT, your most experienced intubator, RSI with cricoid, left-uterine displacement, pre-oxygenate well, surgeons scrubbed/draped before induction, and a failed-airway backup plan. Because she's a full stomach, wake her up before extubating.
Common mistakes
  • Treating a C-section as 'just a quick case' — have the GA conversion and failed-airway plan ready before you start.

Concepts adapted for AnesthesiaHub from “Anesthesia Made Easy” (Jeff Steiner, DO, MBA) and standard anesthesia references, re-expressed in this site's own words. Educational use only — always verify doses against primary sources and your institution's protocols.